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Budesonide, with high first-pass metabolism, has been tried as an induction agent instead of prednisolone to minimize steroid-related side effects

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Researchers study both naturally occurring and synthetic peptides to gain greater insight into how these molecules influence different systems and mechanisms

However, in complexes with positively charged molecules, including certain DAMPs, DNA can become immunogenic (142)

By optimizing trial design, participant recruitment, and site performance, these technologies are helping to accelerate timelines while enhancing trial precision

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