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Parker LJ, Ciccone S, Italiano LC, Primavera A, Oakley AJ, Morton CJ, et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 188.Giacco F., Brownlee M

Therefore, to overcome this drawback, a formulation form that can be injected intramuscularly, subcutaneously or intravenously should be developed at a later stage

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Building on these findings, we combined functional and phenotypic cell death assessments, transcriptomic data, and syngeneic tumor models in murine melanoma and colorectal cancer cell lines to demonstrate that lipophilic statins uniformly promote ferroptosis by depleting GPX4 and that statin-induced ferroptosis augments antitumor immune responses following -PD1 checkpoint blockade