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Microbiota-derived trimethylamine N-oxide predicts cardiovascular risk after STEMI

doi: 10.1016/s0163-7827(00)00005-9

Heute ist man sich sicher, dass diese Acyl-Carnitin-Verbindung ein protektiver Mechanismus ist, der die Zelle vor Stress (= Anreicherung von Lipid-Spezies) schtzt

Supports fluid balance and protects key enzymes involved in energy production

Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity In contrast to the well-established roles of PPARgamma and PPARalpha in lipid metabolism, there is limited understanding of PPARdeltas involvement in this process

Hereditary causes include genetic defects in the metabolism of amino acids, cholesterol, and fatty acids, such as propionyl-CoA carboxylase deficiency (aka propionic acidemia) and medium chain acyl-CoA dehydrogenase deficiency (36)