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ROS and hormonal signaling are tightly intertwined where ROS acts as intrinsic growth and development signals activating many essential developmental processes, such as root hair growth, root elongation and gravitropism (thru auxin), stomatal closure (thru abscisic acid, ABA), lignin synthesis (thru jasmonic acid), leaf shape, trichome development, seed germination, etc

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However, these compounds have thus far not had been subjected to clinical trials, possibly because of unwanted side effects, including lower Ca 2+ transport or increased heme-oxygenase (HO-1) levels (Konorev et al., 2002)

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