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The function of neuromelanin is currently unknown, but it is relevant that the substance accumulates in the SN of aging primates [4, 21]

Often depleted by birth control pills

Standard initial treatment for patients: Without neurological involvement: 1000 g intramuscularly three times a week for two weeks

AtGRXcp, an Arabidopsis chloroplastic glutaredoxin, is critical for protection against protein oxidative damage

The gap between standard and encapsulated forms is significant enough that delivery method is arguably as important as dose

By initiating membrane lipid peroxidation, mitochondrial ROS may also promote the accumulation of pathological extracellular A peptides and intraneuronal hyperphosphorylated tau protein, leading to the formation of AD-defining A plaques and neurofibrillary tangles, which further exacerbate mitochondrial defects (139, 140)