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Then, the EEPT value is close to zero, and therefore, the EEPT/NEPT coefficient tends towards zero, which brings the solution of the equation closer to (or equal to) the value of 1

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For example, if a patient with Crohns disease is on an anti-TNF therapy and has had some improvement in their intestinal symptoms but still has active perianal fistulas or persistent inflammation on endoscopy, I may consider adding a second agent to target a different pathway. In contrast, if that same patient had no meaningful improvement at all despite adequate drug levels [in the blood], I would be more likely to switch to a different class of therapy rather than stack," Ali says

If fatigue doesnt improve after a few weeks, follow up with your clinician to confirm the diagnosis, check whether the dose and form are appropriate, and look for other contributors such as iron deficiency, thyroid issues, sleep problems, or medication effects

However, while these management options can be coded, some of them may have limitations imposed by payers on the frequency of care and by whom the care may be rendered