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In particular, the high-dose combination elevated SOD and catalase far above metformin-treated and normal control levels, highlighting its antioxidant enzyme induction potential

In a carotid artery ligation mouse model, RvD2 and MaR1 markedly reduced VSMC proliferation, limited neutrophil and macrophage infiltration, and exerted antifibrotic effects by promoting macrophage polarization toward the reparative M2 phenotype [73]