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Description
Hericium erinaceus, commonly known as lions mane mushroom, has gained increasing scientific interest due to its rich composition of bioactive compounds and diverse health-promoting properties

Methods In this study, we design a two-in-one ferroptosis-inducing nanoplatform using iron-based metal-organic framework (MOF) that combines iron supply and GPX4 deactivation by loading the small molecule buthionine sulfoxide amine (BSO) to block de novo GSH biosynthesis, which can achieve sustainable GSH elimination and dual ferroptosis amplification
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KD offers neuroprotection for dopaminergic neurons, provides an alternative fuel source to the brain, and optimizes cerebral glucose metabolism

Vitamin B12 plays an important role in maintaining energy levels, supporting nerve health, and boosting cognitive function
