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A study showed that combining diet, myo-inositol, and D-chiroinositol may accelerate fat loss in women with PCOS-related obesity

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This negative trial ended clinical development

The competition between NAD + salvage and the methylation of NAM suggests that NNMT may reduce the oxidation of fuel and increase the storage of fat by regulating the formation of NAD + (Trammell and Brenner, 2015)

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