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Structure and function of pancreatic lipase-related protein 2 and its relationship with pathological states

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These effects may require pharmacologic plasma levels, often exceeding 1000 mol/L, which can only be reliably achieved via intravenous administration or improved delivery systems such as liposomes (Carr and Cook, 2018

Non-HDL-C levels correlated highly with apoB levels in 1665 healthy subjects ( Y = 1.404 X + 9.48, R 2 = 0.94, p apoB) increases with greater insulin resistance, suggesting that apoB underestimates LDL particle number in patients with insulin resistance that is typically accompanied by hypertriglyceridemia

Epub 2009 Jan 17

Finally, delineating tissue-preferential effects is essential to determine whether improvements in IR arise primarily from reduced hepatic lipid content or also involve amelioration of pancreatic steatosis and skeletal muscle lipid metabolism