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(2016) along with semi-automatic quantification tools developed specifically for use with this model (Montava-Garriga et al., 2020)
The IDO1 gene is located on chromosome 8p11.21 and is composed of 10 exons that encode a protein of 403 amino acids
The World Health Organization (WHO) categorizes lung tumors into two major groups: non-small cell lung cancer (NSCLC), which represents 80%85% of all cases, and small cell lung cancer (SCLC), accounting for the remaining 15% (Travis et al., 2015)
The synthetic analog replicates a 15-amino acid sequence and has been studied for its potential to influence fibroblast activity, angiogenesis, nitric oxide pathway regulation, and extracellular matrix remodeling across experimental models
