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Effect of NAC on oocyte quality Meiotic and cytoplasmic maturation of oocytes is negatively impacted by inflammation and oxidative stress, which results in decreased fertilization and implantation [23]

Excess cytosolic Ca 2+ directly stimulates L-type voltage-gated calcium channels (VGCCs) in uterine smooth muscle, leading to pathological hypercontractility that is clinically expressed as severe dysmenorrhea, a hallmark symptom of endometriosis (EMs)

This evidence demonstrates that various clinical and pathological symptoms of AD, including the deposition of A plaques, the formation of neurofibrillary tangles, metabolic dysfunction, and cognitive decline, arise following a prolonged period of gradual accumulation of oxidative damage (Rao et al., 2020) This section will further discuss the two hypotheses on the association between A and oxidative stress

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A comparison of the gut microbiota among adult patients with drug-responsive and drug-resistant epilepsy: an exploratory study