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Description
The gene encoding for leptin is mutated in genetically obese (ob/ob) mice

Preclinical evidence suggests it may promote: increased lipid utilization reduced fat storage improved metabolic efficiency However: these observations come mainly from laboratory research

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Available online at: (Accessed June 18, 2009)

Similarities between insulin and IGF-1 suggest the possible role of IGF-1 in the pathological process of this syndrome, therefore several studies have attempted to correlate IGF-1 plasma levels with MetS
