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Nephrol Dial Transplant , 2003

[Abstract]2025 Jul;31(7):e70508

Molecular Formula: CHN (as cation) Molecular Weight: 159.21 g/mol (free base) CAS Number: 1220-83-3 Mechanism: Selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in the methylation of nicotinamide and regulation of NAD+ precursor availability and cellular energy metabolism Sequence Classification: Small-molecule quaternary ammonium compound Purity Analysis: 98% by HPLC This molecular data supports advanced research into NNMT inhibition, NAD+ biosynthesis pathways, adipogenesis, and metabolic homeostasis studies

Silymarin decreases connective tissue growth factor to improve liver fibrosis in rats treated with carbon tetrachloride

J Biol Chem 282, 1737517386 (2007)

The concern for rectal injury caused by posterior perforation of the capsule is significantly higher, due to the inside-out approach that occurs with laser enucleation of the prostate