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Alzahrani AS, Mukhtar N, Aljomaiah A, Aljamei H, Bakhsh A, Alsudani N, Elsayed T, Alrashidi N, Fadel R, Alqahtani E, Raef H, Butt MI, Sulaiman O (2021) The impact of COVID-19 viral infection on the hypothalamic-pituitary-adrenal axis

It is the most common adult leukemia and often presents asymptomatically with isolated, striking leukocytosis
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10.1016/j.intimp.2024.112010 108 XieY.LvZ.LiW.LinJ.SunW.GuoH.et al (2025)
this upregulation is linked to ENTPD5 expression, which has been suggested to play an important role in promoting melanoma cell proliferation, motility, and metastasis through IGF1R signaling