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After deparaffinization, sections were stained with Mayer's hematoxylin solution (Wako, Tokyo, Japan) for 10 min, and then stained with eosin alcohol solution (Wako) for 4 min

By blocking TREK-1, PE-22-28: Increases neuronal excitability : Reduces potassium efflux, depolarizing neurons toward firing threshold Enhances serotonergic transmission : TREK-1 is expressed on serotonergic neurons in the dorsal raphe nucleus

" Ingredients: Aqua (Deionized Water), Triticum Vulgare (Wheat Germ) Oil, Cetyl Alcohol, Stearyl Alcohol, Ceteareth-20, Propylene Glycol, Polyacrylamide, C13-14 Isoparaffin, Laureth-7, Isopropyl Myristate, Glycerin, Caprylic/Capric Triglyceride, Lecithin, Dimethicone, Copper Tripeptide-1, Xanthan Gum, Tetrasodium EDTA, Phenoxyethanol, Ethylhexylglycerin Alcohol Free, Sulfate Free, Paraben Free Warnings: Avoid contact with eyes
