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After weight loss, the ECM is in a compromised state

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The effective functioning of the epidermal barrier and the protection of the body from external factors are contingent on the preservation of skin homeostasis 2

E.NguyenT.1992Molecular cloning and heterologous expression of a cDNA encoding a mouse glutathione S-transferase Yc subunit possessing high catalytic activity for aflatoxin B1-8,9-epoxide.285173180 38

In contrast, in models with GLS mutations, glutamate metabolism in tumor cells is restricted, which increases Gln concentration in the microenvironment and T-cell uptake and antitumor activity

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