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In some cases, elevated serum MMA (and tHcy) concentrations have been reduced by vitamin B12 therapy, thus confirming vitamin B12 deficiency (Lindenbaum et al., 1990
So, we need other ways to help cartilage heal better

However, the effect of DEG treatment on these modifications differed over time, with 24 h DEG treatment required for substantive changes on lipoylation, although PDHc-E2 glutarylation was observed at 6 h (Extended Data Fig

Oxidative stress and cellular pathologies in Parkinsons disease
EHA 2022, Abstract 887, 2022

More studies showed that the elimination of old damaged cells would process during fasting, and more active immune cells would be generated when fasting ended (35)
