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596 Notably, memory loss in the PS2APP mouse AD model has been linked to astrocyte Ca 2+ hypoactivity due to reduced expression by astrocytes of the calcium sensor, STIM1

Among these, GPX4 has a unique capacity to selectively interact with the polar head of phospholipids, facilitating its association with bilayer membranes [47, 48]

Figure 1 2.3 Clinical evidence supporting the involvement of iron dysregulation in Alzheimers disease progression Recent clinical and imaging studies indicate that iron dysregulation is an active contributor to early Alzheimers disease (AD) pathogenesis rather than a mere byproduct of late neurodegeneration

In geometry, it is a polygon with at least one interior angle greater than 180

Malinauskas, T., Aricescu, A