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Deoxypodophyllotoxin (DPT) inhibits NSCLC cell proliferation and induces necroptosis via mitochondrial dysfunction and ROS generation, proving effective in drug-sensitive and resistant cells (Wu et al

Recent advancements in nanotechnology-driven formulations, such as nanoencapsulation, offer promising solutions to mitigate risks while enhancing therapeutic outcomes

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By enhancing SIRT6 activity, fucoidans improve DNA repair mechanisms and reduce tissue senescence, particularly in the kidney and lung, thereby extending healthspan in aged mice 192,193

These results indicate that the cysteine transport system of EAAC1 is a notable feature, and one that is independent of the other EAATs, for neuronal GSH synthesis