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Neurochemical abnormalities in chronic fatigue syndrome: a pilot magnetic resonance spectroscopy study at 7 Tesla

Its role in fatty-acid oxidation is well established in basic science, and its been used clinically for decades in settings where mitochondrial function needs explicit support
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Longer and more saturated fatty acids will favour higher Tm values, whereas unsaturation and short fatty acids will favour lower Tm values

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20:3n-6 is metabolized to 20:4n-6, which produces prostanoids, leukotrienes, hydroxy fatty acids, lipoxins (aspirin-dependent), and F2 isoprostanes
