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These interactions manifest clinically as insulin resistance, adrenal insufficiency, thyroid dysfunction, and reproductive abnormalities, all of which may accelerate liver injury and complicate management

In the present study, we aimed to investigate how age-related changes in metabolite levels contribute to AD pathology, with a specific focus on the role of palmitoyl-L-carnitine

The insulin and insulin-like growth factor-I receptor substrate IRS-1 associates with and activates phosphatidylinositol 3-kinase in vitro

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