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6,48 In this regard, new evidences suggest that both disorders share many etiopathogenic links, which are presented below

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RTMS exerts multifaceted neuroprotective effects in AD model mice by attenuating glutamate excitotoxicity via the PI3K/Akt/GLT-1 signaling pathway

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with the gene usually designated NFE2L2 ), as are enzymes involved in the regeneration of NADPH (glucose 6-phosphate 1-dehydrogenase (G6PD), 6-phosphogluconate (PGD), isocitrate dehydrogenase 1 (IDH1) and malic enzyme 1 (ME1)) and those involved in the synthesis of GSH (glutamatecysteine ligase catalytic (GCLC) and glutamatecysteine ligase modifier (GCLM) subunits) [3641] suggests that the Nrf2 transcription factor makes a substantial contribution to the efficiency of reduction of H 2 O 2 by PRDX

Correlation between serum carnitine levels and erythrocyte osmotic fragility in hemodialysis patients