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[10] As a drug target [edit] Inhibitors of MTHFR and antisense knockdown of the expression of the enzyme have been proposed as treatments for cancer

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These and other examples demonstrate the great potential for discovery of natural compounds that can be used as pharmaceuticals that may affect GSH homeostasis

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doi: 10.1089/jmf.2013.2965

on the other hand, increased levels of VEGF-A in the brain may lead to the production of pro-inflammatory cytokines, neuroinflammation and BBB stratification