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2021;22(9):e51683

Diminishing return vs 10 mg

Schenck et al., Statements Author contributions CAS and YM performed experiments and analyzed data

Pineal Gland Signaling and Melatonin Rhythm Modulation The AEDG sequence was originally derived from epithalamin, a polypeptide extract of the bovine pineal gland, and a significant body of research has investigated its interactions with pineal function specifically melatonin synthesis and circadian rhythm regulation

Most notably, around 20% of CNs treated with the highest dose of the topical formulation exhibited a 50% reduction in volume