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The presence of the mutants and the lack of unintentional mutations were confirmed by sequencing the entire GSTP1 coding region (The Center for Applied Genomics, The Hospital for Sick Children, Toronto, ON)

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Products containing large amounts of fiber or those that expand in the stomach may worsen nausea or early satiety when combined with tirzepatide's gastric-slowing effects

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Gao Y, Van Haren MJ, Buijs N, Innocenti P, Zhang Y, Sartini D, Campagna R, Emanuelli M, Parsons RB, Jespers W (2021b) Potent inhibition of nicotinamide N-methyltransferase by alkene-linked bisubstrate mimics bearing electron deficient aromatics