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All three opioid receptor are highly expressed in the pallidum (Le Merrer et al., 2009)

High selectivity for GH release with minimal impact on other hormones (ACTH, cortisol, prolactin) [1] [3]

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Recently, lithium, a mood stabilizer commonly prescribed for bipolar disorder [144], has been shown to reverse abnormal cellular phenotypes in MARK2-mutated neural progenitor cells

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in the latter circumstance, saturation of metabolism may be the explanation