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Platelet activation, aggregation, and subsequent intra-arterial thrombosis are important steps in atherosclerotic thrombosis, and enhanced platelet reactivity is associated with the degree of terminal organ injury and poor prognosis ( 2+ release from intracellular stores ( in vivo can potentially lead to thrombosis, and within the physiological range of TMAO concentration observed in human and animal models, the effect of TMAO on platelet function is dose-dependent

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Muscle Recovery A double-blind, placebo, crossover study found that 2 g of L-carnitine had positive effects and significantly attenuated markers of purine metabolism, free radical formation, muscle tissue disruption, and muscle soreness after physical exertion.[4] A randomized, placebo-controlled study suggested L-carnitine can improve exercise tolerance and muscle strength while decreasing lactic production

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