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This type of study can often lead to subsequent investigations of the function of the candidate biomarker and hence is called hypothesis generating

DDS also reduced antioxidant capacity (TEAC, GSH, SOD, CAT) and increased oxidative damage (lipid peroxidation, iron accumulation), while ALA restored antioxidant levels and reduced oxidative stress
A multi-centre, double-blind, 12-week, randomized, placebo-controlled trial of adjunctive N-Acetylcysteine for treatment-resistant PTSD

A pilot study of add-on oral triheptanoin treatment for children with medically refractory epilepsy
Many substances associated with oxidative stress increase during aging and in patients with chronic inflammatory diseases, like COPD

L., Colton, H
