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Pemetrexed administered intraperitoneally at doses of 0.1 mg/kg/day to male mice (approximately 0.0006 times the recommended human dose based on BSA) resulted in reduced fertility, hypospermia, and testicular atrophy

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Central sensitisation causes distorted pain perception, possibly through facilitation within the spinal cords dorsal horns and the loss of antinociceptive inhibition from the brain

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I've always believed that everything happens for a reason, so, even though it very nearly killed me, perhaps it was meant to happen so I am now in a position to help others