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The mechanism involves the dependence of key family members of AP-1 and NFB on Nrf1 and Nrf2 for their expression (Yang et al., 2005a)
Unlike other tissues in the body, cartilage does not have a blood supply, making it difficult to repair itself once damaged

Similarly, our findings revealed that MitoQ could attenuate pulmonary fibrosis by enhancing PINK1/Parkin-mediated mitophagy both in vivo and in vitro
Lipoic Acid: A Multifunctional Antioxidant

To do this, astrocytes activate the citrate-pyruvate shuttle (CPS) (Figure 2C