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Besides the BBB, NPs can be engineered to overcome the complex signalling, cellular, and tissue-specific barriers within the brain that shape their fate and efficacy to reach the target site

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Cysteine is the rate-limiting constituent in the production of reduced glutathione, and it can be replaced by its precursor NAC

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N-Acetyl-Cysteine (NAC)is a source of the conditionally essential amino acid L-cysteine and a precursor to the tripeptide glutathione

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2019;123(2):e263e272

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