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16 The aim of this paper is to review the evidence for the use of B12 in clinical practice beyond the replacement in deficiency

About 50-60% of people have a genetic variation that does not allow this process to be completed

In Drosophila , both overexpression and knockdown of HDAC4 impair memory, suggesting that HDAC4 is both a repressor when in excess and essential for normal memory function [47]

Because vitamin B12 contains the mineral cobalt, compounds with vitamin B12 activity are collectively called cobalamins
Energy production (metabolism) Neurological (brain) function Vitamin B12 plays a key role in the normal functioning of the brain and nervous system

On the other hand, lysozymes possess immunomodulatory, anti-inflammatory functions [171] and they can modulate the microflora of the gut [172, 173]
