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The association between varicocele and elevated oxidative stress levels has been well-established, with multiple studies confirming higher oxidative stress in infertile men with varicocele compared to their fertile counterparts and those with idiopathic infertility [246,247,248,249,250]

doi: 10.1111/bcpt.12679

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While short-term or single-cycle AAS use is often followed by partial or complete restoration of hypothalamicpituitarygonadal (HPG) axis function, prolonged or repeated exposure to supraphysiological doses is associated with an increased risk of incomplete or delayed recovery