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Description
Behavioral deficit, oxidative stress, and mitochondrial dysfunction precede tau pathology in P301S transgenic mice
The mechanism is consistent with general lymphoid tissue growth under elevated IGF-1 exposure
The studys authors noted that increases in GH and IGF-I levels produced by CJC-1295 DAC were dose-dependent, meaning that in the context of that particular study, higher doses of CJC-1295 produced greater rises in GH and IGF-1 levels than lower doses
46 ChekerovR.HilpertF.MahnerS.El-BalatA.HarterP.De GregorioN.et al (2018)
35 IqbalK.LiuF.GongC
& Jensen, S
