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The mechanism is proposed to involve G-protein coupled receptor signaling, but definitive identification of the functional receptor has not been published

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TGF-beta receptors: In and beyond TGF-beta signaling

These results suggested that the increase in the amount of glutathione in the ER caused the reductive shift in the ER after proteasome inhibition

Wang K, Shao X, Zhang K, Wang J, Wu X, Wang H