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Treatment with high dose vitamin B12 been shown to be safe for more than 50 years Out of fear of overdosing vitamin B12, treatment is often reduced to below the frequency that is needed by the patient, or, even worse, treatment is stopped completely

This lipid modification allows binding to albumin in the bloodstream

Otherwise, supporting your overall health by bridging any potential nutrient gaps with the use of a multivitamin such as Performance Lab NutriGenesis Multi would also be beneficial

According to Cant et al., Cell Metabolism , increased NAD stimulates PGC-1 activity, driving mitochondrial biogenesis and substrate flexibility

Summary of Laboratory Tests to Assess Vitamin B12 Deficiency