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Kwong JC, Carr D, Dhalla IA, Tom-Kun D, Upshur RE: Oral vitamin B12 therapy in the primary care setting: a qualitative and quantitative study of patient perspectives

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Bacteria-derived hydroxocobalamin (OHCbl) and CNCbl are converted in humans to useful coenzyme forms to support metabolic processes such as mitochondrial methyl malonyl coenzyme A mutase conversion of methylmalonic acid (MMA) to succinate to link lipid and carbohydrate metabolism, and activation of methionine synthase, the rate-limiting step in the synthesis of methionine