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A clinical study treating crow's feet with GHK-Cu formulations showed substantial wrinkle reduction after 12 weeks, with skin biopsies confirming increased collagen in the upper dermis

10.1038/mt.2008.214 Mol

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Re face A stereoheterotropic face of a trigonal atom is designated Re if the ligands of the trigonal atom appear in a clockwise sense in order of priority when viewed from that side of the face