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One trial showed that short-term NR administration has some beneficial effects in healthy elderly individuals 185 , and another showed positive results in patients with ALS 93,186,187

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Further, NO-system immobilization was not achieved (L-NAME and L-arginine did not oppose each others effect), which might indicate the essential involvement of other systems as well [59,70]

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doi: 10.1016/j.atherosclerosis.2008.09.015

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