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6H), confirming that Ssu72 directly dephosphorylates p-GSK3 (Ser9) in vitro

However, when it is disturbed, neurodegeneration can result (Parakh et al., 2013

Melanin is what gives pigment to hair and eyes and colour to the skin
In 2006, they were awarded the Nobel Prize in Physiology and Medicine for their RNAi technology

Thus, while each platform has demonstrated proof-of-concept efficacy, the choice of design must balance responsiveness, stability, and biosafety to ensure clinical applicability