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In a randomized placebo-controlled trial, metformin treatment was associated with a mean decrease in vitamin B 12 concentration by 19% and an increase in homocysteine concentration by 5% [52]

If your symptoms are mild and your calendar is clear, pulling the covers over your head and getting some extra sleep might be all you need

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That decline correlates with slower wound healing, thinner skin, and reduced regenerative capacity

If you follow a plant-based diet, you'll likely need fortified foods or supplements to maintain healthy levels

Mild fluid retention that can cause swelling, particularly in the ankles