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Outside-In Because CNS pathology, especially that of white matter, so often involves damage to both myelin, glia, and axons, universally accompanied by an immune response, it is extremely difficultbut at the same time very importantto disentangle the precise sequence of events that trigger MS

We have ascertained a beneficial effect, but the full mechanism remains elusive

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Ethanol as a Prodrug: Brain Metabolism of Ethanol Mediates its Reinforcing Effects