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TABLE 6 Critical appraisal of included studies

Signaling pathways in cancer-associated fibroblasts and targeted therapy for cancer

Regarding the biological significance of the ASCT2 inhibitor, Schulte et al

doi: 10.1111/j.1743-6109.2010.01705.x 14 DerosaGTinelliCD'AngeloAFerraraGBonaventuraABianchiLet al

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Their findings suggest that disrupting the barrier could provide a new therapeutic technique for halting tumor growth and preventing metastasis [74]
