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Description
Studies have found that up to 87% of people with migraine have low DAO levels, and supplementing with DAO or following a low-histamine diet may reduce symptoms

The hepatic extraction ratio refers to the fraction of drug removed from the blood on a single pass through the liver, a value which is equal to 1-f H
DOI: 10.1002/eji.1830261229 40

However, it is not universally safe for everyone , and it should never be given without prior evaluation

Large national surveys paint a nuanced picture
doi: 115
