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This process attenuated GPX4s inhibitory function against ferroptosis, effectively blocking the GPX4/GSH pathway

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Released ATP is converted to adenosine via ectonucleotidases, activating adenosine receptor A2a (A2aR) and inducing IL-10 production (129)

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One study investigating the role of endogenous PAF C-16 during M.tb infection in mice found that there was no significant difference in mortality between PAFR deficient (PAFR / ) and wild-type control mice when infected with M.tb and similar M.tb loads were observed in the lungs and liver (Weijer et al., 2003)