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Oxidative stress is a primary driver of neuronal damage in aging Nrf2 activation provides broad protection
Duggan et al., enrolled 439 overweight/obese postmenopausal women between the ages of 50 and 75 in a 12-month randomized controlled trial to determine the effects of diet and/or exercise on oxidative stress biomarkers [152]
Abnormal epigenetic landscapes drive cancer therapeutic resistance Alterations in the patterns of post-translational modifications (PTMs) have been extensively linked to cancer, whether considering the global level across the entire genome or the genetic information and functional status of cells
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