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HeLa or HCT116 cells were seeded on a 96-well plate at 5000 cells/well

The extrinsic pathway involves interaction of cell surface death receptors [for example, Fas/CD95

Future research should focus on scaling up production, optimizing dosing regimens, and conducting clinical trials to confirm these findings and explore the broader applicability of this technology in ocular drug delivery

10.1016/j.jep.2023.116471 60 LiuZ.ZhouZ.AiP.ZhangC.ChenJ.WangY

The degree of structural damage present initially may influence durability of response

Thus, the researchers concluded that this interaction may potentially shield islets against the detrimental effects of proinflammatory cytokines, which might be released by activated macrophages or as a result of the transplantation procedure itself