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This patient has an extremely high risk of needing dialysis at some point in his life

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J Neuroinflammation 21:55 [DOI] [PMC free article] [PubMed] [Google Scholar] 40.Jing X, Shi H, Zhang C, Ren M, Han M, Wei X, Zhang X, Lou H (2015) Dimethyl fumarate attenuates 6-OHDA-induced neurotoxicity in SH-SY5Y cells and in animal model of Parkinsons disease by enhancing Nrf2 activity

The good thing is that side effects disappear when the user stops taking vitamin B12, so effects are easily reversible
