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Two timing strategies dominate the research: Morning fasted: Administering IGF-1 LR3 in a fasted state maximizes receptor sensitivity

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There was also a dose-dependent effect on BW gain, but no effect on total IGF-I levels, IGFBPs, or serum markers of bone formation and resorption

10.1016/0003-9861(90)90327-U [DOI] [PubMed] [Google Scholar] Carroll LS, Abdul-Rahim AH, & Murray R (2017)